NANOFLEXTM – Advanced Joint Support

The science behind NANOFLEXTM is what makes it so unique. I first learned of it in 2016 during a business trip to England.

NANOFLEXTM offers a completely different non-invasive solution to joint support with its innovative nanotechnology-driven topical delivery system.

Inside the joint capsule, it addresses joint support with a groundbreaking new approach providing enhanced biolubrication and protection of the cartilage surface.


The Science of NANOFLEXTM

NANOFLEXTM is composed of a very long sounding name – Ultra Deformable SequessomeTM Vesicles or UDSV.

There are billions of these tiny oily droplets in NANOFLEXTM, and after the patented nanotechnology engineering process, these UDSV become extremely flexible and attracted to water.

Once NANOFLEXTM starts to dry on the skin or coat, the tiny size, hydration, and flexibility of the UDSV allow them to be drawn through the skin and into the joint capsule itself.

Nano Cells
NANOFLEX Joint Support - Inside the Joint

Once inside the joint capsule, the second fascinating aspect of this joint product goes to work.

Historically, joint lubrication supplements or injections work on improving the viscosity of the synovial fluid in the joint, but NANOFLEXTM works in a very unique way.

As the UDSV enter the joint capsule, they accumulate on the cartilage surfaces on both sides of the joint, protecting the cartilage tissue. This provides a slippery surface, so when the joint is compressed, the two sides of the joint have a completely new source of biolubrication.

Imagine a row of tennis balls sitting on the cartilage that rolls back and forth as the cartilage tissue is compressed. Every time you apply NANOFLEXTM, you replenish this slippery layer. And this ultimately helps relieve stiffness, tightness, and mobility issues with healthy joint function.

What is Nanotechnology?

Nanotechnology and nanoscience are the study and application of extremely small things and can be used across all the other science fields, such as chemistry, biology, physics, materials science, and engineering.

What is Biolubrication?

Biolubrication plays a crucial role in assisting the sliding contacts in many organs in the human body. Notable examples are the joints, the skin surface, the eye, the mouth, and the gastrointestinal tract, the lungs, and the red blood cells.

Reduced lubrication leads to increases in friction and adhesion between the surfaces in contact, which may lead to the surfaces becoming stuck and wearing, ultimately leading to irritation, pain, and trauma.

Joint lubrication supplements involve a complex and adaptive set of lubrication mechanisms:

  1. The smoothness of the cartilage lining of the bone surfaces.
  2. Synovial fluid – a lubricating hydrogel of collagen fibrils.
  3. Hyaluronic Acid.
  4. Glycoproteins (lubricin) and water.
  5. A weeping mechanism by which joint pressure releases synovial fluid into the interspacing liquid film separating the cartilage surfaces.


NANOFLEXTM can be used on older horses, dogs, and cats who may need extra support as they age, and their normal joint function starts to degrade.

Horses, in particular, through their various competitive disciplines, are subjected to repeated high-stress movements on their joints, which can result in accelerated changes to the function of their joints.

How Horse Joints Work

Whatever the species, the basic structure and function of all mammalian joints are similar in that articular cartilage covers and protects the ends of the bones. This cartilage provides a smooth, low-friction gliding surface that allows free movement of the joint.

Articular cartilage is made up of water, collagen, and a complex group of proteins called Proteoglycans, which consist of hyaluronic acid and long chains of “glycosaminoglycans,” often referred to as “GAGs.”

Proteoglycans trap and hold water, forming a cushion of dense fluid at the ends of the bones, enabling movement and absorbing shock when the joint bears weight.

Articular cartilage has no blood supply. It is solely dependent on another joint component, synovial fluid, to deliver vital components and act as a lubricant and cushion between the bones.

Age and work degrade the quality of the synovial fluid, which in turn diminishes the quality of the articular cartilage. The joint then loses its protection against friction, concussion, and the invasion of destructive inflammatory cells.

NANOFLEXTM and Horse Joints

NANOFLEXTM is a joint lubrication supplement designed to give joints non-invasive support and relief from friction, rubbing, and stiffness and remove restrictions. Biolubrication and nanotechnology combine to lubricate the joint, allowing your horse to move more freely and easily.

It’s important to remember that if you ride in a competitive discipline, the range of movements your horse does causes significant stress on the joints and soft tissues.

The earlier steps are taken to offer additional support to your horse’s joints, the better the chances of maintaining healthy joint function over time.